Invasive Micropapillary



So you have heard the words “breast cancer” and “invasive micropapillary” and you turned to the internet and googled “it.”  You’ve been surfing around online trying to make sense of what is happening to you, to sort it out and to put together some sort of plan. I know, I did the same thing.  That is why I started breast cancer MyStory.  It is here for you so you’d have a soft space online to land when the hard diagnosis of breast cancer hits.  Take your time to wander our site.  In all your frantic worries of the moment, don’t forget to stop and smell the flowers (thus the photo reminder to the left that I took outside my son’s apartment in Chicago). We are here for you 24/7 and you are welcome anytime.



 The following information is from

Micropapillary Carcinoma of the Breast

Micropapillary breast carcinoma (or invasive micropapillary carcinoma IMPC) is a type of otherwise ‘typical’ invasive ductal carcinoma which exhibits a unique and characteristic growth pattern. Representing approximately 6% of all breast cancers, the invasive micropapillary breast carcinoma ‘pattern’ is one in which the tumor develops fairly prominent clear spaces, into which the tumor cells form into cohesive clusters. Invasive micropapillary breast carcinoma is a very aggressive form of breast cancer, with a very high rate of lymph node metastasis.(The rate of lymph node involvement is estimated at between 75% and 100%). Skin invovlement (skin retraction) is another occassional feature of invasive micropapillary carcinoma of the breast, and is observed in about 20-23% of all cases. The average age range for development of invasive micropapillary breast carcinoma is typically around the early 60s. Invasive micropapillary carcinoma of the breast is discovered as a palpable mass in over 90% of cases. And, for no apparent reason, micropapillary breast carcinoma tends to affect the left breast more frequently than the right breast, or about 65% of the time.


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2 Responses to “Invasive Micropapillary” Subscribe

  1. Ken August 1, 2014 at 8:34 am #

    Sorry to read about your brother, and even more sorry there have not been any responses.

    My wife was recently diagnosed with invasive micropapillary carcinoma, after her mastectomy. Only one sentinel lymph node was removed. We’re trying to research this particular type of cancer, and it seems there is very little out there. What is out there does not sound encouraging. “Rare” and “aggressive” seem to be the typical descriptions. The doctor initially prescribed 4 cycles of TC, but now thinks an additional 4 cycles of AC might be appropriate. We would like to hear feedback on treatment and prognosis for this disease. Thanks!

  2. Robert Harris May 15, 2014 at 1:15 am #

    I have no inspirational message. This post is prompted by the daily frustration expressed by my brother who was diagnosed with moderately differentiated micropapillary cancer of the breast. After surgery he was told that the excised mass as well 20 nodes were cancerous. His oncologist recommended a course of T+AC. Over the 11 infusions of taxol, he learned how toxic taxol is. By his 11th infusion his temperature dropped below 96 and has remained there for nearly 2 weeks. He has refused further treatment, believing that the regimen he’s being prescribed is off the shelf and that there’s no supporting science to support the treatment. He’s spoken with numerous oncologists and can find no one who can put him in touch with micropapillary cancer patients, male or female, who are alive after treatment. In brief, where’s the science supporting a therapy aimed at micropapillary CB and are there any MCB patients who have survived treatment?

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